直線上に配置
薬・・・消化器系
June 1 2002
以下は「Lippincott's Review for NCLEX-RN 7th Edition」のp323-p355の問題の中からでてきたものを解説中心にまとめたものです。
  purpose how to use side effect other
antacid        
ranitidine
(Zantac)
for peptic ulcer 1T・・・at bedtime
2T・・・morning & bedtime
4T・・・1-3H after every meals + bedtime
constipation ・空の胃に内服するとduration of the drug's actionが短縮する
→そのため食事の後1-3時間に内服

・他の薬と併用するときは他の薬内服後2Hくらいで内服する
cimetidine
(Tagamet)
for peptic ulcer
 (胃酸を減らす働き)

for hiatal hernia
 (食道炎をおさえ、heartburnに効く)

(histamine receptor antagonist)
  paradoxic central nervous system
→Ataxia (impared vision, gait, thinking)
 
aluminum hydroxide
(Amphojel)
for peptic ulcer   constipation  
magnesium hydroxide
(milk of magnesia)
for hiatal hernia   diarrhea  
sucralfate
(Carafate)
for peptic ulcer 空腹時にP.O.   食前1H or 食後2H

眠前
の4回/d服用
for GERD        
bethanechol
(Urecholine)
cholinergic drug
to increase lower esophagial sphincter pressure facilitating gastric emptying
  urinary urgency
diarrhea
abdominal cramping
hypotension
salivation ↑
 
metoclopramide hydrochloride
(Reglan)
to increase lower esophagial sphincter pressure facilitating gastric emptying

antiemetic効果
  sedation, 眠気
→alcoholやdrive禁


・extrapyramidal reaction (involuntary movements of the face, eyes, or extremities)
・Parkinsonism-like reaction
 
for ulcerative colitis        
sulfasalazine
(Azulfidine)
抗炎症性腸疾患治療薬   結石を作る
→水をたくさん飲む

gastrointestinal distress
→食後に服用する
Hrはアルカリ性になりorange-yellowになる
抗菌剤        
neomycin 腸管手術の前処置
to reduce the number of intestinal bacteria

肝硬変
for blocking ammonia formation
     
下剤        
psyllium hydrophilic mucilloid
(Metamucil)
bulk laxative
for 憩室炎
     
mineral oil lubricating & aoftning the stool      
止寫薬        
diphnoxylate with atropine sulfate
(Lomotil)
antidiarrhea      
鎮痛剤        
meperidine
(Demerol)
narcotic analgesics
for 胆管・胆嚢炎の痛み
  convulsion, tremor コデインやモルヒネは、よりbiliary duct spasmをひきおこし、pain↑
propantheline bromide
(Pro-Banthine)
antispasmodic drugs
for the intense pain associated with pancreatitis


anticholinergic drug
for 胆嚢炎
  urinary retention, constipation, flushed dry skin, mouth, nose, throat 筋肉をスムーズにし、胃の動きや膵酵素分泌を減少させることにより、痛みを緩和する
インターフェロン        
Interferon alfa-2b for Hepatitis B   flu-like syndrome  
利尿剤        
spironolactone
(Aldactone)
treat for the ascites   K↑  
肝性脳症治療剤        
lactulose
(Cephulac)
trapping and expelling ammonia in the feces   increased bowel movements  
肝硬変          
albumin act to move fluid
血管外から血管内へ
    fluid overloadに注意
sign・・
shortness breath,
moist crackles