直線上に配置
薬・・・呼吸器系
June 1 2002
以下は「Lippincott's Review for NCLEX-RN 7th Edition」のp301-p322の問題の中からでてきたものを解説中心にまとめたものです。
  purpose how to use side effect other
鼻炎        
psudoephedrine
(Sudafed)
for nasal decongestant

central nervous systemに働きかける
  restlessness, dizziness
anxiety, insomnia…
 overuse*するとrebound effectとしてnasal congestion↑へ導くことあり
due to reflex vasodilation

*more than 3 days
結核        
streptomycin
(aminoglycoside)
    eight cranial nerve damage (ototoxicity)
<symptom>
vertigo, tinnitus, hearing loss, ataxia
 
INH(isoniazid)     peripheral neuritis
→VB6 intake

hepato toxic drug
→avoid alcohol
→avoid rich tyamino food

oral contraceptive effective down↓↓
 
PAS (para-aminosalicylic acid)     gastrointestinal disturbance  
Ethambutol hydrochloride
(Myambutol)
    optic neuritis  
Rifampin 抗生剤   hepato toxic drug  
COPD        
theophilline to relax of bronchial smooth muscle      
肺気腫        
aminophylline to relax of bronchial smooth muscle      
Asthma        
corticosteroids anti-inflammetory effect
・act to decrease edema
・act to decrease mucus secretion
    ステロイド吸入はoral thrushのside effectあり
→after each using pt should rinse their mouth !
meraproterenol
(Alupent)
β-adrenergic receptors   不整脈・頻脈・anginal pain  
flunisolide
(AeroBid)
oral inharent corticosteroids   oral thrush, a fungal infection  
multiple drug treatment
(combination of antituberculosis)
combination chemotherapy
advantage
 ・to slow the rate at which organisms develop drug resistance
 ・more effective than single-drug therapy
 ・not to reduce side effect
multiple drugs are given to
 ・interrupt the cell growth cycle at different points
 ・decrease resistance to a chemotherapy agent
 ・minimize the toxicity associated with use of a high dose of a single agent

*抗がん剤と副作用に対する薬の組み合わせという意味ではない